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The MagLab is funded by the National Science Foundation and the State of Florida.

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Tag: Health research

How MRI Machines Work

Watch how radio waves and strong magnets combine to create pictures of the inside of our bodies.


MRI: A Guided Tour

These awesome diagnostic tools, powered by strong superconducting magnets, save countless lives with their ability to pinpoint tumors and other abnormalities.


Let’s play SciBall!

This sports and science mash up features new geeky games inspired by the cool things scientists study in high-field magnets. 


High Fields at Home

A lot of the research conducted in powerful magnets ends up having a powerful effect on our day-to-day lives.


Stroke of Genius

Using high-field MRI, researchers are working to improve recovery in stroke victims.


Felix Bloch

Physicist Felix Bloch developed a non-destructive technique for precisely observing and measuring the magnetic properties of nuclear particles.


Leon Cooper

Leon Cooper shared the 1972 Nobel Prize in Physics with John Bardeen and Robert Schrieffer, with whom he developed the first widely accepted theory of superconductivity.


Willem Einthoven

Willem Einthoven invented a string galvanometer that could be used to directly record the electrical activity of the heart.


Luigi Galvani

Luigi Galvani was a pioneer in the field of electrophysiology, the branch of science concerned with electrical phenomena in the body.


Paul Lauterbur

Chemist Paul Lauterbur pioneered the use of nuclear magnetic resonance (NMR) for medical imaging.


Duchenne Machine – 1850

French physician Guillaume Benjamin Amand Duchenne invented a device that electrically stimulates muscles. The apparatus gave him new insight into neuromuscular disorders, earned him the epitaph of "father of electrotherapeutics," and entertained the courts of Europe.


Electrocardiograph – 1903

If TV medical dramas have taught us anything, it's how to recognize the heart's characteristic peaks and valleys crawling across monitors in emergency rooms. These images represent the electrical activity of the beating heart as recorded by an electrocardiograph, a machine that revolutionized diagnostic cardiology and helped garner a Nobel Prize.


Pacemaker – 1960

Many heads, hands and hearts contributed to the development of this lifesaving device.


World’s Strongest Human MRI

Pack a sack lunch and load up! We're hitting the road to learn how this massive magnet tracks sodium moving through your brain.


Across the Tree of Life: Radiation Resistance Gauged by High-Field EPR

This high-field EPR study of the H-Mn2+ content in the bacterium Deinococcus Radiodurans provides the strongest known biological indicator of cellular ionizing radiation resistance between and within the three domains of the tree of life, with potential applications including optimization of radiotherapy.


Making a Non-Heme Oxoiron(IV) Complex a Better Oxidant

This work investigates a series of oxoiron complexes that serve as models towards understanding the mechanism of catalysis for certain iron-containing enzymes.


Scientists Observe Molecular Movements in T Cells

Insights into the structure and movement of T cell surface proteins could lead to new ways to fight cancers, infections and other diseases.


Tuberculosis Metalloproteins Probed With High-Field Electron Magnetic Resonance

High-magnetic-field time-resolved electron magnetic resonance was used to probe the unusual manganese/iron complex that is believed to play a role in the disease-producing activity of tuberculosis “superbugs,” revealing a vacancy in the vicinity of the manganese that is believed to enable a target molecule to bind to the metal ion.


Targeted annotation of peptides by selective infrared multiphoton dissociation mass spectrometry

Protein oxidative damage is a common occurrence in a number of diseases, including cancer, neurodegenerative, and cardiovascular disease. Yet, little is known about its contribution to these illnesses. We developed a new technique, utilizing an infrared laser in combination with a mass spectrometer, to selectively identify sites of oxidation in complex protein mixtures. This sensitive and rapid platform may outperform current techniques and thus shed light on the involvement of oxidative damage in each of these diseases.


Identification of abnormal hemoglobin from human blood

Precise determination of hemoglobin sequence and subunit quantitation from human blood for diagnosis of hemoglobin-based diseases.


Ultrahigh Performance Molecular Imaging using the 21T ICR Magnet

Combining spatial imaging technology with ultrahigh performance FT-ICR mass spectrometry provides users with the unique ability to create tissue images of identified biomolecules. This technology will be applied to understand human health and disease.


The Blood Proteoform Atlas: A reference map of proteoforms in human blood cells

A new Blood Proteoform Atlas maps 30,000 unique proteoforms as they appear in 21 different cell types found in human blood. The MagLab's 21 tesla FT-ICR mass spectrometer contributed nearly a third of the atlas' proteoforms.


More Accurate Diagnosis for Multiple Myeloma

New technique could lead to precise, personalized cancer diagnosis and monitoring.


Imaging Current Flow in the Brain During Transcranial Electrical Stimulation

Scientists measured the first in vivo images of stimulated current within the brain using an imaging method that may improve reproducibility and safety, and help understand the mechanisms of action of electrical stimulation.


"Molecular Sieves" Could Lead to Much Cheaper Gas Production

Combining high-field NMR with infrared microscopy, scientists learned more about how gas diffuses in a novel class of molecular sieves that could one day be used for gas separation.


Brain Waste Pathway Found

Little is known about the path of metabolic waste clearance from the brain. Here, high-field magnetic resonance images a possible pathway for metabolic waste removal from the brain and suggests that waste clearance may be one reason why we sleep.


MRI Detects Brain Responses to Alzheimer's Disease Plaque Deposits and Inflammation

Magnetic Resonance Imaging (MRI) of mouse models for Alzheimer’s disease can be used to determine brain response to plaque deposits and inflammation that ultimately disrupt emotion, learning, and memory. Quantification of the early changes with high resolution MRI could help monitor and predict disease progression, as well as potentially suggest new treatment methods.


Mystery of the Origin of MRI Signal in Stroke Solved

MRI scans taken after a stroke show brightness around the injury, the origins of which have been a long-standing and vexatious mystery for scientists. This work suggests these MRI signal changes result from fluid changes in glial cell volumes, results that could advance our ability to distinguish reversible and irreversible stroke events or provide a better understanding for other disorders such as Parkinson's, Alzheimer's, and mood or sleep disorders. 


Atomic-Level Insights into How Polymers Improve Protein Therapeutics

Using NMR, researchers determined a molecular model of a protein-polymer conjugate, providing new insights into how polymers can be used to make protein drugs more robust.


Metabolic Assessment of Migraines Using Ultra-High Magnetic Fields

The causes of migraines are not well understood, with treatment limited to addressing pain rather than its origin. Research conducted with hydrogen MRI is attempting to identify the "migraine generator."


Uncovering the Secrets of Fungal Cell Walls

With unprecedented sensitivity and resolution from state-of-the-art magnets, scientists have identified for the first time the cell wall structure of one of the most prevalent and deadly fungi.


Scientists Identify Potential Biomarker for Brain Diseases

With advanced techniques and world-record magnetic fields, researchers have detected new MRI signals from brain tumors.


Imaging Enzyme Active Site Chemistry Using Multiple Fields up to 35.2T

This new technique for mapping out atom placements in the active site of enzymes could unlock the potential for finding new therapeutics.


Finding Water Molecules with Important Biological Activity

A new 17O solid-state NMR technique, employed on the highest-field NMR spectrometer in the world (the 36 T Series Connected Hybrid), identifies water molecules in different layers of a model membrane for the first time.


ICR FAIR Data: Improves Understanding of Protein Fragmentation

Reuse of the MagLab's Ion Cyclotron Resonance facility data improved understanding of protein fragmentation and aided the design and release of new algorithms and software tools. This is representative of a new type of MagLab user: A Data User – who accesses MagLab data from public data repositories to advance independent research goals. 


NMR FAIR Data: Phase-Separation Properties of an RNA-Binding Protein

Evolutionary biologists reused FAIR data generated at the MagLab's NMR facility to model an RNA-binding protein in mammals dating back 160 million years and to explore how evolution and natural selection have influenced the structure of the protein. Their work suggests new strategies for improving our understanding of this protein, which could lead to improved therapies for neurodegenerative diseases like ALS.


Study on Motor Neuron Proteins Lands on Cover of Cell

Research sheds new light on the formation of harmful structures that can lead to neurodegenerative diseases.


MagLab’s Newest World-Record Magnet Open for Science

State-of-the-art ion cyclotron resonance magnet system offers researchers significantly more power and accuracy than ever before.


National MagLab to Receive $184M NSF Renewal Grant

The National Science Foundation announces five-year funding grant for continued operation of the world’s most powerful magnet lab.


Scientists Discover Cheap Fluid That Could Lead to Cheap MRIs

Finding could make pricey, massive scanners a thing of the past.


International Science Leaders Meet at the MagLab

The visit marked the first time the Group of Senior Officials for Global Infrastructures has met in the United States.


Best Research of 2017

35 highlights out of 423 reports representing the best of life sciences, chemistry, magnet science and technology, and condensed matter physics.


Researchers Discover Sodium-Migraine Link Before Pain Occurs

Findings clarify the role of sodium increase early in migraines and point to the region where symptoms may start.


$3.3 Million NIH Grant to Fund MagLab Research

Researchers at the National MagLab will study the role sodium plays in this painful disease and test treatments that could offer relief.


MagLab Scientists Capture Molecular Maps of Animal Tissue With Unprecedented Detail

Enabled by a world-record instrument, the images convey vast amounts of data that could be useful in health and pharmaceutical research.


"Water Wires" May Play Bigger Role in Cell Functions

New insights challenge current understanding of how ion transport through some cell membranes works.


New Agreement to Bolster Industry Partnerships

Tallahassee Company MagCorp to Partner with National MagLab.


Understanding How Pathogenic Fungi Build Their Carbohydrate Armor

Molecular architecture of fungal cell walls and the structural responses to stresses revealed in new paper.


FT-ICR Facility Gets New World-Record Magnet

The MagLab and the Bruker Corporation have installed the world’s first 21 tesla magnet for Fourier Transform Ion Cyclotron Resonance (FT-ICR) mass spectrometry.


Combatting COVID: Digging Deeper for COVID-Causing Proteins

Researcher digs below the coronavirus's membrane in search of another layer of infection-causing proteins. 


Combatting COVID: Setting the Science Straight on a COVID Protein

For membrane protein expert Tim Cross, solving the structure of a misunderstood protein put retirement on hold.


Combatting COVID: COVID Drug-Target Dragnet

The virus that causes COVID-19 has thousands of potential drug targets. A global team is on a hunt for the best candidates.


Combatting COVID: Stemming the Spread of COVID

A team of experts believes stem cells could be a route to a fast, effective therapy.


Border Patrol

Borderline biology? Crossover chemistry? Scientists are working on the edge of their fields to learn how proteins police the walls of cells. 


Nanocages May Hold Key to Advances in Health, Energy

Scientists are working to understand the complex reactions that create nanocages, work that could help uncage new drug delivery and energy options.  


Nano Drug Delivery is Rocket Science

How is nano science advancing door-to-door drug delivery, but on the cellular level?


Double Whammy

What happens when a kid with ADHD sustains a concussion? Using high-field magnets, researchers are working to find out.


Mapping the Brain's Weird Web of Waste

Using advanced MRI, a mechanical engineer tackles the question: "Why do you have these big fluid spaces in your head?"


Combating Cancer

Scientists are using powerful magnets to learn how to better detect, treat and track the second leading cause of death worldwide.


Meet the 21 Tesla ICR Magnet

Used to perform complex chemical analysis, this magnet offers researchers the world's highest field for ion cyclotron resonance mass spectrometry.


Meet Kendra Frederick

It's freaking hard to examine proteins closely in their native habitat. With the help of very clever magnet instrumentation, University of Texas scientist Kendra Frederick is up for the challenge.


Meet Andreas Neubauer

Andreas Neubauer took the extended stay option during his recent trip to the MagLab. After all, you can't rush art — especially when it's mixed with science.


A Mouse

Why are scientists putting a mouse in the MagLab's magnets? A scientist is developing an MRI technique to detect kidney disease that lights up the organs' metabolism.


Hemoglobin

ICR technology helps identify new kinds of hemoglobin abnormalities.


Peat Soil

Looking for clues on climate change, a scientist digs up the dirt on peat from around the world.


From Kansas to MIT: Long's Long Road to a Career in Chemistry

Each day at work, Long, tackles the twin duties of providing administrative leadership for a growing program, and her own scientific research.



Last modified on 10 August 2022