Keto Knowledge

Keto Knowledge Are ketogenic diets helpful in controlling non-alcoholic fatty liver disease? This new NMR work offers a look into dietary influences on lipid synthesis.

Overall hepatic metabolism is significantly altered by diet.

Spontaneous Surprise

Electrons are shown to spontaneously jump to the same quantum state in this atomically-thin semiconductor.

Left: The tungsten di-selenide (WSe2) monolayer-on-fiber assembly used for optical absorption studies in 60 tesla magnetic fields., Right:  Discrete jumps in the absorption indicate emptying and spontaneous filling of specific quantum states (the “valley”states).

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Research Initiatives

Research Initiatives - Materials

MATERIALS

Scientists use our magnets to explore semiconductors, superconductors, newly-grown crystals, buckyballs and materials from the natural world — research that reveals the secret workings of materials and empowers us to develop new technologies.

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Research Initiatives - Energy

ENERGY

Scientists here are working to optimize petroleum refining, advance potential bio-fuels such as pine needles and algae, and fundamentally change the way we store and deliver energy by developing better batteries.

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Research Initiatives - Life

LIFE

With the world’s strongest MRI magnet, scientists here study everything from living animals to individual cells, from proteins to disease-fighting molecules found in plants and animals — work that could improve treatment of AIDS, cancer, Alzheimer’s and other diseases.

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Latest Science Highlights


  • Using Magnetic Resonance to Probe Lipid Synthesis in Response to Ketogenic Diet
    18 November 2020
    Using Magnetic Resonance to Probe Lipid Synthesis in Response to Ketogenic Diet

    Non-alcoholic Fatty Liver Disease and its progression to more serious diseases will become the main cause for liver transplant in the next 5 years. Here, researchers used deuterium magnetic resonance to study dietary influences on lipid synthesis demonstrating that high fat ketogenic diets significantly slow de novo lipogenesis, a process by which excess carbohydrates are covered into fatty acids and stored as triacylglycerols.

  • Spontaneous "Valley Magnetization" in an Atomically-thin Semiconductor
    18 November 2020
    Spontaneous "Valley Magnetization" in an Atomically-thin Semiconductor

    Interactions between electrons underpin some of the most interesting – and useful -- effects in materials science and condensed-matter physics. This work demonstrates that, in the new family of so-called "monolayer semiconductors" that are only one atomic layer thick, electron-electron interactions can lead to the sudden and spontaneous formation of a magnetized state, analogous to the appearance of magnetism in conventional materials like iron.

  • Prefractionation of Intact Proteins for Mass Spectrometry
    16 October 2020
    Prefractionation of Intact Proteins for Mass Spectrometry

    Analysis of intact proteins using mass spectrometry is a difficult task that can be simplified by prefractionation, a process in which protein mixtures are separated into simpler fractions based on size. Here, researchers developed a new method, PEPPI-MS, which uses low-cost materials and common lab equipment to make an important protein separation strategy widely available.

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Featured Publications


Using Magnetic Resonance to Probe Lipid Synthesis in Response to Ketogenic Diet , M.S. Muyyarikkandy, et al., The FASEB Journal, 2020;00:1–18 See Science Highlight or Read online 

Spontaneous "Valley Magnetization" in an Atomically-thin Semiconductor, J. Li, et al., Phys. Rev. Lett., 125, 147602 (2020) See Science Highlight or Read online 

Spin-Charge Interconversion at Near-Terahertz Frequencies, P. Vaidya, Science, 368, 160-165 (2020) See Science Highlight or Read online 

Tunable Weyl Fermions in Chiral Tellurene in High Magnetic Fields, G. Qiu, Nature Nanotechnology, 15, 585–591 (2020) See Science Highlight or Read online 

Deuterium Magnetic Resonance Can Detect Cancer Metabolism by Measuring the Formation of Deuterated Water, R. Mahar, Nature Scientific Reports, 10 (1), 8885 (2020) See Science Highlight or Read online 

High magnetic fields reveal hidden magnetism in a cuprate superconductor, M. Frachet, Nature Physics, 16, 1745-2481 (2020) See Science Highlight or Read online 

Smart Non-Linear Transport Technique Expands the Frontier of Superconductor Research, M. Leroux., Physical Review Applied, 11, 054005 (2019) See Science Highlight or Read online 

Inducing Magnetic Ring Currents in Non-Magnetic Aromatic Molecules: A Finding From the 25 T Split-Florida Helix , B. Kudisch, et al., Proceedings of the National Academies of Science, 117 (21), 11289-11298 (2020) See Science Highlight or Read online 

Molecular magnetic building blocks , J.-L. Liu, et al., Angew. Chem., February (2020) See Science Highlight or Read online 

Exploring Topological Semimetals in High Magnetic Fields , J. Liu, et al., Phys. Rev. B, 100, 195123 (2019) See Science Highlight or Read online 

MRI detects brain responses to Alzheimer’s disease plaque deposits and inflammation, L.M. Colon-Perez, et al., NeuroImage, 202, 116138 (2019) See Science Highlight or Read online 

Analytical tool for in vivo triple quantum MR signals, V.D. Schepkin Zeitschrift fur Medizinische Physik, 29 (4), 326-336 (2019) See Science Highlight or Read online