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Preparing Proteins

To enable important chemical analysis on proteins, scientists developed a new technique that uses low-cost materials and equipment commonly found in biochemistry laboratories.

Preparing Proteins

The Makeup of MOFs

Using the largest NMR magnet in the world, researchers found new details on the structure of metal organic frameworks, work that could change how drugs are delivered or data is stored in the future.

The α-Mg3(HCOO)6 metal-organic framework that contains twelve unique oxygen sites.

Boost for Spin Liquid Candidate

The case that ruthenium trichloride is a quantum spin liquid just got stronger, making it a possible building block for future quantum computers.

Scientists working at the National MagLab have found evidence of a quantum spin liquid in ruthenium trichloride (RuCl3).

Science Night Goes Virtual

Join us each month for a free, family-friendly science activity delivered LIVE on Zoom right to your devices.

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Research Initiatives

Research Initiatives - Materials


Scientists use our magnets to explore semiconductors, superconductors, newly-grown crystals, buckyballs and materials from the natural world — research that reveals the secret workings of materials and empowers us to develop new technologies.

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Research Initiatives - Energy


Scientists here are working to optimize petroleum refining, advance potential bio-fuels such as pine needles and algae, and fundamentally change the way we store and deliver energy by developing better batteries.

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Research Initiatives - Life


With the world’s strongest MRI magnet, scientists here study everything from living animals to individual cells, from proteins to disease-fighting molecules found in plants and animals — work that could improve treatment of AIDS, cancer, Alzheimer’s and other diseases.

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Latest Science Highlights

  • Prefractionation of Intact Proteins for Mass Spectrometry
    16 October 2020
    Prefractionation of Intact Proteins for Mass Spectrometry

    Analysis of intact proteins using mass spectrometry is a difficult task that can be simplified by prefractionation, a process in which protein mixtures are separated into simpler fractions based on size. Here, researchers developed a new method, PEPPI-MS, which uses low-cost materials and common lab equipment to make an important protein separation strategy widely available.

  • Probing Metal Organic Frameworks with 17O NMR at 35.2 T
    16 October 2020
    Probing Metal Organic Frameworks with 17O NMR at 35.2 T

    Metal-organic frameworks (MOFs) are porous materials with high surface areas that can host a variety of different guest molecules, leading to applications in catalysis, drug delivery, chemical separation, fuel cells, and data storage. In order to design better MOFs, knowledge of their molecular-level structures is crucial. At the MagLab, the highest-field NMR spectrometer in the world was used to probe the complex structures of MOFs both "as built" and as they exist when other "guest" molecules are inserted inside the framework.

  • Spin-Charge Interconversion at Near-Terahertz Frequencies
    6 October 2020
    Spin-Charge Interconversion at Near-Terahertz Frequencies

    This work reports the first observation of the dynamical generation of a spin polarized current from an antiferromagnetic material into an adjacent non-magnetic material and its subsequent conversion into electrical signals

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Featured Publications

Spin-Charge Interconversion at Near-Terahertz Frequencies, P. Vaidya, Science, 368, 160-165 (2020) See Science Highlight or Read online 

Tunable Weyl Fermions in Chiral Tellurene in High Magnetic Fields, G. Qiu, Nature Nanotechnology, 15, 585–591 (2020) See Science Highlight or Read online 

Deuterium Magnetic Resonance Can Detect Cancer Metabolism by Measuring the Formation of Deuterated Water, R. Mahar, Nature Scientific Reports, 10 (1), 8885 (2020) See Science Highlight or Read online 

High magnetic fields reveal hidden magnetism in a cuprate superconductor, M. Frachet, Nature Physics, 16, 1745-2481 (2020) See Science Highlight or Read online 

Smart Non-Linear Transport Technique Expands the Frontier of Superconductor Research, M. Leroux., Physical Review Applied, 11, 054005 (2019) See Science Highlight or Read online 

Inducing Magnetic Ring Currents in Non-Magnetic Aromatic Molecules: A Finding From the 25 T Split-Florida Helix , B. Kudisch, et al., Proceedings of the National Academies of Science, 117 (21), 11289-11298 (2020) See Science Highlight or Read online 

Molecular magnetic building blocks , J.-L. Liu, et al., Angew. Chem., February (2020) See Science Highlight or Read online 

Exploring Topological Semimetals in High Magnetic Fields , J. Liu, et al., Phys. Rev. B, 100, 195123 (2019) See Science Highlight or Read online 

MRI detects brain responses to Alzheimer’s disease plaque deposits and inflammation, L.M. Colon-Perez, et al., NeuroImage, 202, 116138 (2019) See Science Highlight or Read online 

Analytical tool for in vivo triple quantum MR signals, V.D. Schepkin Zeitschrift fur Medizinische Physik, 29 (4), 326-336 (2019) See Science Highlight or Read online 

Nuclear Spin Patterning Controls Electron Spin Coherence , C.E. Jackson, et al., , Chem. Sci., 10 (36), 8447-8454 (2019) See Science Highlight or Read online 

Influence of a nematic phase on high-temperature superconductivity , P. Reiss, et al., Nature Physics, 28, Oct (2019) See Science Highlight or Read online