Nuclear Magnetic Resonance and Magnetic Resonance Imaging / Spectroscopy

900 MHz 105 mm Bore NMR Magnet

Users Michael Harrington (Huntington Medical Research Institute). left, and Eduard Chekmenev (Vanderbilt University), right , work with staff scientist Victor Schepkin on the 900.

900 MHz 105 mm Bore NMR Magnet

4.7 Tesla 33 cm MRI/S System

Located at AMRIS at our University of Florida campus in Gainesville.

4.7 Tesla 33 cm MRI/S System

Technology Development

We are world leaders in designing and building probes and other NMR-MRI/S instrumentation.

An NMR probe.

High-resolution Imaging

Viewing images obtained with the 4.7 tesla MRI scanner at the Advanced Magnetic Resonance Imaging and Spectroscopy Facility at the University of Florida in Gainesville.

Viewing images obtained with the 4.7 tesla MRI scanner at the Advanced Magnetic Resonance Imaging and Spectroscopy Facility  at the University of Florida in Gainesville.

NMR - MRI/S techniques and instruments are available at two different MagLab facilities in Florida: The NMR-MRI/S Facility at MagLab headquarters near Florida State University in Tallahassee and the Advanced Magnetic Resonance Imaging and Spectroscopy Facility (AMRIS) housed within the McKnight Brain Institute at the University of Florida in Gainesville.

Working in tandem, these facilities combine unique magnets, equipment and expert scientific support with advanced capabilities for technique and instrumentation development. About 20 spectrometers and scanners are available for use with an array of solid state, solution state, MRI/S (animal and human), MR microscopy and diffusion capabilities and techniques.

map of Tallahassee and Gainesville, Florida

 

Our unique instruments include the 900 MHz 105 mm bore magnet — the world's strongest MRI machine — at our FSU location and a 600 MHz, triple-resonance probe at AMRIS that appears to deliver the highest mass sensitivity of any probe at any frequency, enabling natural-products research when sample size is small or limited.

Magnet time is free and allocated on the basis of scientific peer review; we accept proposals throughout the year. While many users conduct their experiments in person, an increasing number also work remotely with the help of our dedicated staff.

HOW TO APPLY

Our magnets are open to all scientists — for free — via a competitive process; we accept proposals throughout the year.

  1. Prepare documentation
    A proposal and prior results report are required.
  2. Create a user profile
    Returning users simply need to log in.
  3. Submit a request online
    Upload files and provide details about the proposed experiment.
  4. Report your results
    Submit a 1-page report and info on publications resulting from your experiment.

Read the User Proposal Policy for complete guidelines or contact NMR-MRI/S Facility Director Tim Cross or AMRIS Facility Director Joanna Long.

AMRIS

 

Latest Science Highlight



Featured Publications

A Method for Dynamic Nuclear Polarization Enhancement of Membrane Proteins

A.N. Smith, et al., Angew. Chem. Int. Ed., 54, 5, 1542-1546 (2015) Read online …


Acyl-CoA oxidase complexes control the chemical message produced by Caenorhabditis elegans

X.X. Zhang, et al., P. Natl. Acad. Sci. U.S.A., 112, 13, 3955-3960 (2015) Read online …


C-13 NMR Metabolomics: INADEQUATE Network Analysis

C.S. Clendinen, et al., Anal. Chem., 87, 11, 5698-5706 (2015) Read online …


Shaped Ceria Nanocrystals Catalyze Efficient and Selective Parahydrogen Enhanced Polarization

E.W. Zhao, et al., Angew. Chem. Int. Ed., Accepted Manuscript, 1 (2015) Read online …


Investigation of the subcellular architecture of L7 neurons of Aplysia californica using magnetic resonance microscopy (MRM) at 7.8 micronsLee

C.H. Lee, et al., Scientific Reports, 5, 11147 (2015) Read online …


Dimensionless, Scale Invariant, Edge Weight Metric for the Study of Complex Structural Networks

L.M. Colon-Perez, et al., PLOS ONE, 10, 7, :e0131493 (2015) Read online …

See more AMRIS publications

NMR-MRI/S Facility

 

Latest Science Highlight


  • A Decade of Science on the Ultra-Wide-Bore 900 MHz NMR Spectrometer
    16 July 2015
    A Decade of Science on the Ultra-Wide-Bore 900 MHz NMR Spectrometer

    Ten years ago the 900 Ultra-Wide Bore magnet became available to an international user community for Nuclear Magnetic Resonance spectroscopy and Magnetic Resonance Imaging at the National High Magnetic Field Lab. Since then 69 publications have been published from this instrument spanning many disciplines and the number of publications per year continues to increase with 26 in just the past 18 months demonstrating that state of the art data continues to be collected on this superb magnet.

    Read more...

Featured Publications

Sodium 3D COncentration MApping (COMA 3D) using 23Na and proton MRI

M.L. Truong, et al., Journal of Magnetic Resonance, 247 (2014) Go to Developed Software or Read online …


Structure of CrgA, a cell division structural and regulatory protein from Mycobacterium tuberculosis, in lipid bilayers

N. Das, et al., Proc Natl Acad Sci USA, vol. 112 no. 2. (2014) See Science Highlight or Read online …


Multimodal nanoprobes to target cerebrovascular amyloid in Alzheimer’s disease brain

K.M. Jaruszewski, et al., Biomaterials, 35(6):1967-76 (2014) Read online …


Binding of MgtR, a Salmonella Transmembrane Regulatory Peptide, to MgtC, a Mycobacterium tuberculosis Virulence Factor: A Structural Study

F.L. Jean-Francois, et al., J. Mol. Biol., 426:436-446. PMID: 24140750. (2014) Read online …

See more NMR-MRI/S Facility publications


For more information contact NMR-MRI/S Facility Director Tim Cross or AMRIS Facility Director Joanna Long

Last modified on 17 August 2015