Matthew Edward Merritt

Associate Professor

UF, AMRIS Affiliated Faculty & Staff


Contact Information

Phone (352) 294-8397
Fax (352) 392-4535
Building UF

Publications and Scientific Activities


    1. Hyperpolarized C-13 MRI: Path to Clinical Translation in Oncology Kurhanewicz, J.; Vigneron, D.B.; Ardenkjaer-Larsen, J.H.; Bankson, J.A.; Brindle, K.; Cunningham, C.H.; Gallagher, F.A.; Keshari, K.R.; Kjaer, A.; Laustsen, C.; Mankoff, D.A.; Merritt, M.E.; Nelson, S.J.; Pauly, J.M.; Lee, P.; Ronen, S.; Tyler, D.J.; Rajan, S.S.; Spielman, D.M.; Wald, L.; Zhang, X.L.; Malloy, C.R.; Rizi, R. Neoplasia, 21, 1, 1-16 (2019)
    2. Kinetic Analysis of Hepatic Metabolism Using Hyperpolarized Dihydroxyacetone Kirpich, A.; Ragavan, M.; Bankson, J.A.; McIntyre, L.M.; Merritt, M.E. JCIM, 59, 1, 605-614 (2019)
    3. Metabolomic profiles differ among unique genotypes of a threatened Caribbean coral Lohr, K.E.; Khattri, R.B.; Guingab-Cagmat, J.; Camp, E.F.; Merritt, M.E.; Garrett, T.J.; Patterson, J.T. Nature Scientific Reports, 9, 6067 (2019)


    1. In vivo hyperpolarization transfer in a clinical MRI scanner Von Morze, C.; Reed, G.D.; Larson, P.E.; Mammoli, D.; Chen, A.P.; Tropp, J.; Van Criekinge, M.; Ohliger, M.A.; Kurhanewicz, J.; Vigneron, D.B.; Merritt, M.E. Magnet. Reson. Med., 80, 2, 480-487 (2018)
    2. Sensitivity enhancement for detection of hyperpolarized C-13 MRI probes with H-1 spin coupling introduced by enzymatic transformation in vivo Von Morze, C.; Tropp, J.; Chen, A.P.; Marco-Rius, I.; Van Criekinge, M.; Skloss, T.W.; Mammoli, D.; Kurhanewicz, J.; Vigneron, D.B.; Ohliger, M.A.; Merritt, M.E. Magnet. Reson. Med., 80, 1, 36-41 (2018)
    3. Probing cardiac metabolism by hyperpolarized 13C MR using an exclusively endogenous substrate mixture and photo-induced nonpersistent radicals Bastiaansen, J.A.M.; Yoshihara, H.A.I.; Capozzi, A.; Schwitter, J.; Gruetter, R.; Merritt, M.E.; Comment, A. Magnet. Reson. Med., 79, 5, 2451-2459 (2018)
    4. A novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity Wu, C.Y.; Satapati, S.; Gui, W.; Wynn, R.M.; Sharma, G.; Lou, M.; Qi, X.; Burgess, S.C.; Malloy, C.R.; Khemtong, C.; Sherry, A.D.; Chuang, D.T.; Merritt, M.E. J. Biol. Chem., 293, 25, 9604-9613 (2018)
    5. The effect of Ho 3+ doping on 13 C dynamic nuclear polarization at 5 T Sirusi, A.; Suh, E.H.; Kovacs, Z.; Merritt, M. Phys. Chem. Chem. Phys., 20, 2, 728-731 (2018)


    1. Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2-13C]dihydroxyacetone Marco‐Rius, I.; von Morze, C.; Sriram, R.; Cao, P.; Chang, G.Y.; Milshteyn, E.; Bok, R.A.; Ohliger, M.A.; Pearce, D.; Kurhanewicz, J.; Larson, P.E.; Vigneron, D.B; Merritt, M. Magnet. Reson. Med., 77, 1, 65-73 (2017)
    2. Multiband Spectral-Spatial RF Excitation for Hyperpolarized [2-C-13]Dihydroxyacetone C-13-MR Metabolism Studies Marco‐Rius, I.; Cao, P.; von Morze, C.; Merritt, M.; Moreno, K.X.; Chang, G.Y.; Ohliger, M.A.; Pearce, D.; Kurhanewicz, J.; Larson, P.E. and Vigneron, D.B. Magnet. Reson. Med., 77, 4, 1419-1428 (2017)
    3. A comprehensive analysis of myocardial substrate preference emphasizes the need for a synchronized fluxomic/metabolomic research design Ragavan, M.; Kirpich, A.; Fu, X.; Burgess, S.C.; McIntyre, L.M. and Merritt, M.E. American Journal of Physiology-Heart and Circulatory Physiology, 312, 6, H1215-H1223 (2017)
    4. Hyperpolarized Δ-[1-C-13]gluconolactone as a probe of the pentose phosphate pathway Moreno, K.X.; Harrison, C.E.; Merritt, M.E.; Kovacs, Z.; Malloy, C.R. and Sherry, A.D. NMR in Biomedicine, 30, 6 (2017)
    5. The NQO1 bioactivatable drug, β-Lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism Silvers, M.A.; Deja, S.; Singh, N.; Egnatchik, R.A.; Sudderth, J.; Luo, X.; Beg, M.S.; Burgess, S.C.; DeBerardinis, R.J.; Boothman, D.A. and Merritt, M.E. J. Biol. Chem., 292, 44, 18203-18216 (2017)
    6. The effect of Ho3+ doping on 13C dynamic nuclear polarization at 5 T Sirusi, A.A.; Suh, E.H.; Kovacs, Z. and Merritt, M.E. Phys. Chem. Chem. Phys., 20, 728-731 (2017)


    1. A general chemical shift decomposition method for hyperpolarized 13C metabolite magnetic resonance imaging Wang, J.X.; Merritt, M.E.; Sherry, D. and Malloy, C.R. Magnet. Reson. Chem., 54, 8, 665-673 (2016)
    2. Accelerated Chemical Shift Imaging of Hyperpolarized C-13 Metabolites Wang, J.X.; Merritt, M.E.; Sherry, A.D. and Malloy, C.R. Magnet. Reson. Med., 76, 4, 1033-1038 (2016)