This facility is charged with developing and exploiting the unique capabilities of Fourier Transform Ion Cyclotron Resonance (FT-ICR) mass spectrometry, and leads the world in instrument and technique development as well as novel applications of FT-ICR mass spectrometry.
The facility features directors for instrumentation, biological applications, environmental, petrochemical applications, and user services as well as a machinist, technician and numerous rotating postdocs who are available to collaborate and/or assist with projects.
The facility provides service operations for sample analysis that requires the ultrahigh resolution and high mass accuracy of FT-ICR. Research falls in the areas of biomolecular analysis, hydrogen-deuterium exchange and environmental and petrochemical analysis. The facility's four FT-ICR mass spectrometers feature high magnetic fields – including the world-record 21 tesla – and are compatible with multiple ionization and fragmentation techniques.
HOW TO APPLY
Our magnets are open to all scientists — for free — via a competitive process and we accept proposals throughout the year.
- Prepare documentation
A proposal and prior results report are required. - Create a user profile
Returning users simply need to log in. - Submit a request online
Upload files and provide details about the proposed experiment. - Report your results
By year’s end, submit a 1-page report and information on publications resulting from your experiment.
Read the User Proposal Policy for complete guidelines or contact Facility Director Chris Hendrickson with questions.
Latest Science Highlight
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Decoding the human proteome with powerful mass spectrometer
28 February 2017
The MagLab’s 21-tesla FT-ICR magnet can identify human proteins far more efficiently than commercial instruments, a boon for medical research.
Featured Publications
Identification and Characterization of Human Proteoforms by Top-Down LC-21 Tesla FT-ICR Mass Spectrometry
L.C. Anderson, et al., Journal of Proteome Research (2017), 16 (2), 1087-1096 See Science Highlight or Read online …
Polar Lipid Composition of Biodiesel Algae Candidates Nannochloropsis oculata and Haematococcus pluvialis from Nano Liquid Chromatography Coupled with Negative Electrospray Ionization 14.5 T Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
Y. Corilo, et al., Energy Fuels (2016), 30, 10, 8270–8276 See Science Highlight or Read online …
DNA Interactions Probed by Hydrogen Deuterium Exchange (HDX) Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Confirm External Binding Sites on the Minichromosomal Maintenance (MCM) Helicase
B. W. Graham, et al., J. Biol. Chem (2016), 291, 12467-12480 See Science Highlight or Read online …
For more information on the ICR Facility, contact one of the individuals listed below:
- Chris Hendrickson, ICR Facility Director
- Amy McKenna, Manager, ICR User Program
- Alan Marshall, Chief Scientist for Ion Cyclotron Resonance