This facility is charged with developing and exploiting the unique capabilities of Fourier Transform Ion Cyclotron Resonance (FT-ICR) mass spectrometry, and leads the world in instrument and technique development as well as novel applications of FT-ICR mass spectrometry.
The facility features directors for instrumentation, biological applications, environmental, petrochemical applications, and user services as well as a machinist, technician and numerous rotating postdocs who are available to collaborate and/or assist with projects.
The facility provides service operations for sample analysis that requires the ultrahigh resolution and high mass accuracy of FT-ICR. Research falls in the areas of biomolecular analysis, hydrogen-deuterium exchange and environmental and petrochemical analysis. The facility's four FT-ICR mass spectrometers feature high magnetic fields – including the world-record 21 tesla – and are compatible with multiple ionization and fragmentation techniques.
HOW TO APPLY
Our magnets are open to all scientists — for free — via a competitive process and we accept proposals throughout the year.
- Prepare documentation
A proposal and prior results report are required.
- Create a user profile
Returning users simply need to log in.
- Submit a request online
Upload files and provide details about the proposed experiment.
- Report your results
By year's end, submit information on publications resulting from your experiment.
Latest Science Highlight
Prefractionation of Intact Proteins for Mass Spectrometry
16 October 2020
Analysis of intact proteins using mass spectrometry is a difficult task that can be simplified by prefractionation, a process in which protein mixtures are separated into simpler fractions based on size. Here, researchers developed a new method, PEPPI-MS, which uses low-cost materials and common lab equipment to make an important protein separation strategy widely available.
Identification of abnormal hemoglobin from human blood
1.1 billion-year-old porphyrins evidence photosynthesis 600 million years earlier than previously established
Targeted Annotation of Peptides by Selective Infrared Multiphoton Dissociation Mass Spectrometry
For more information
Contact one of the individuals listed below or Fellow users who are experts on the use of ICR Facility.