Ion Cyclotron Resonance Facility (ICR)

World-record 21 tesla ICR magnet. World-record 21 tesla ICR magnet. Image: David Barfield

This facility is charged with developing and exploiting the unique capabilities of Fourier Transform Ion Cyclotron Resonance (FT-ICR) mass spectrometry, and leads the world in instrument and technique development as well as novel applications of FT-ICR mass spectrometry.

The facility features directors for instrumentation, biological applications, environmental, petrochemical applications, and user services as well as a machinist, technician and numerous rotating postdocs who are available to collaborate and/or assist with projects.

map of Tallahassee, Florida

The facility provides service operations for sample analysis that requires the ultrahigh resolution and high mass accuracy of FT-ICR. Research falls in the areas of biomolecular analysis, hydrogen-deuterium exchange and environmental and petrochemical analysis. The facility's four FT-ICR mass spectrometers feature high magnetic fields – including the world-record 21 tesla – and are compatible with multiple ionization and fragmentation techniques.

HOW TO APPLY

Our magnets are open to all scientists — for free — via a competitive process and we accept proposals throughout the year.

  1. Prepare documentation
    A proposal and prior results report are required.
  2. Create a user profile
    Returning users simply need to log in.
  3. Submit a request online
    Upload files and provide details about the proposed experiment.
  4. Report your results
    By year's end, submit information on publications resulting from your experiment.

Please review the MagLab User Policies and Procedures before submitting your proposal and experimentor contact Facility Director Chris Hendrickson with questions. View User FAQs.

Latest Science Highlight


  • Prefractionation of Intact Proteins for Mass Spectrometry
    16 October 2020
    Prefractionation of Intact Proteins for Mass Spectrometry

    Analysis of intact proteins using mass spectrometry is a difficult task that can be simplified by prefractionation, a process in which protein mixtures are separated into simpler fractions based on size. Here, researchers developed a new method, PEPPI-MS, which uses low-cost materials and common lab equipment to make an important protein separation strategy widely available.

See more ICR Science Highlights

Featured Publications


Identification of abnormal hemoglobin from human blood

L. He, et al., Clinical Chemistry 65 (8), 986-994 (2019) See Science Highlight or Read online …


1.1 billion-year-old porphyrins evidence photosynthesis 600 million years earlier than previously established

N. Guineli, et al., Proc. Natl. Acad. Sci. 115, 1-9 (2018) See Science Highlight or Read online …


Targeted Annotation of Peptides by Selective Infrared Multiphoton Dissociation Mass Spectrometry

N.B. Borotto, et al., Analytical Chemistry (2017), 89, 8304-8310 See Science Highlight or Read online …


See more ICR publications


For more information

 

Contact one of the individuals listed below or Fellow users who are experts on the use of ICR Facility.

Last modified on 17 April 2020