Protein oxidative damage is a common occurrence in a number of diseases, including cancer, neurodegenerative, and cardiovascular disease. Yet, little is known about its contribution to these illnesses. We developed a new technique, utilizing an infrared laser in combination with a mass spectrometer, to selectively identify sites of oxidation in complex protein mixtures. This sensitive and rapid platform may outperform current techniques and thus shed light on the involvement of oxidative damage in each of these diseases.
Dylan Murray wants to sabotage processes that can lead to neurodegenerative disease.
Research sheds new light on the formation of harmful structures that can lead to neurodegenerative diseases.
A lot of the research conducted in powerful magnets ends up having a powerful effect on our day-to-day lives.
New technique could lead to precise, personalized cancer diagnosis and monitoring.
In the field of inorganic chemistry, magneto-structural correlations have been used to rationally design molecules with desirable properties, and to relate these properties to the electronic and geometric structures. In turn, such studies provide powerful tools for understanding important catalytic processes, as well as elucidating the structures of active sites in metalloproteins. This study reveals an unusually strong sensitivity of the magnetic properties of a CoS4 molecule to minute changes in its structure.
The MagLab’s 21-tesla FT-ICR magnet can identify human proteins far more efficiently than commercial instruments, a boon for medical research.
Explore one of the MagLab's newest world-record magnets through this interactive feature.
Across disciplines, exciting stuff happens along the boundaries between things. What makes those realms so rich for research, and how do magnets shed light on them?
Research sheds important light on the fundamental process of cell division.