Search results (70)

Name Description
Atmospheric Carbon Dioxide from Peat Wetland Ecosystems

Understanding the organic composition of peat wetland soils can determine whether the carbon sources may be converted into carbon dioxide gas, work that could improve existing climate models and better predict the impact of increasing carbon dioxide to wetland ecosystems.

Imaging Enzyme Active Site Chemistry Using Multiple Fields up to 35.2T

This new technique for mapping out atom placements in the active site of enzymes could unlock the potential for finding new therapeutics.

The Blood Proteoform Atlas: A reference map of proteoforms in human blood cells

A new Blood Proteoform Atlas maps 30,000 unique proteoforms as they appear in 21 different cell types found in human blood. The MagLab's 21 tesla FT-ICR mass spectrometer contributed nearly a third of the atlas' proteoforms. 

Understanding How Fungi Build Their Cell Walls for Protection

Scientists have used high-field nuclear magnetic resonance (NMR) to reveal how fungal pathogens use carbohydrates and proteins to build their cell walls (the protective layers outside of the cell). These findings will guide the development of novel antifungal drugs that target the cell wall molecules to combat life-threatening diseases caused by invasive fungal infections.

Restoration of Breathing After Drug Overdose and Spinal Cord Injuries

Respiratory insufficiency is a leading cause of death due to drug overdose or spinal cord injuries. The diaphragm can be stimulated using temporal interference (TI) to restore ventilation with minimally invasive electrodes.

A New Method for Understanding Dynamic Nuclear Polarization

A new method to study how the nuclei of atoms “communicate” with one another in the presence of unpaired electron spins has been developed at the MagLab. Known as hyperpolarization resurgence (HypRes), this method benefits and expands the application of a revolutionary technique known as dynamic nuclear polarization (DNP), which provides enormous signal enhancements in nuclear magnetic resonance (NMR) experiments.

Makeup of Dissolved Organic Matter in Arctic Rivers

Researchers share new insights on the role of seasonality in dissolved organic matter (DOM) composition in large Arctic rivers. 

ICR FAIR Data Improves Understanding of Protein Fragmentation

Reuse of the MagLab's Ion Cyclotron Resonance facility data improved understanding of protein fragmentation and aided the design and release of new algorithms and software tools. This is representative of a new type of MagLab user: A Data User – who accesses MagLab data from public data repositories to advance independent research goals. 

Structure of Boron-Based Catalysts from 11B Solid-State NMR at 35.2T

Measurements performed at the National High Magnetic Field Laboratory provide unique insight into molecular structure of next-generation catalysts for the production of the widely used industrial chemical, propene.

Using Magnetic Resonance to Probe Lipid Synthesis in Response to Ketogenic Diet

Non-alcoholic Fatty Liver Disease and its progression to more serious diseases will become the main cause for liver transplant in the next 5 years. Here, researchers used deuterium magnetic resonance to study dietary influences on lipid synthesis demonstrating that high fat ketogenic diets significantly slow de novo lipogenesis, a process by which excess carbohydrates are covered into fatty acids and stored as triacylglycerols.

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