We are excited to announce that the 53rd edition of the Southeastern Magnetic Resonance Conference (SEMRC) will be held at the University of Florida College of Medicine campus from November 14 – 16, 2025. The SEMRC has a long tradition of bringing together leading scientists to discuss the latest developments in NMR, EPR, and MRI, with a focus on exchanges of ideas and recent magnetic resonance research highlights, including new applications and technique development. Particular emphasis is placed on activities in the Southeastern region, with strong participation of young researchers.